Authors
Ekaterina Orlova, Mariya Rem
For сitation
Orlova E., Rem M. Hand-foot syndrome and nail changes caused by capecitabine chemotherapy. Journal of Clinical Physiology and Pathology (JCPP) 2023; 2 (1): 38-41.
Abstract
The effects of targeted therapy are not limited with cancer cells and, unfortunately, are associated with many and numerous side effects. Dermatological manifestations are one of the most frequently observed, and in severe and/or prolonged they inevitably affect the quality of life of patients. The management of these various side effects is empirical and largely based on expert advice and consensus. Many cytotoxic and biological drugs are the cause of severe dermatological side effects, such as hand-foot syndrome (HFS). An oncological patient with HFS presents relevant symptoms that interfere with daily activities and with adherence to anticancer treatment. Control and treatment of HFRS are the most important goals of improving the quality of life of cancer patients.
Below we present the case of a 62-year-old woman undergoing treatment with capecitabine and paclitaxel for breast cancer.
Keywords
hand and foot syndrome, capecitabine, oncologists, chemotherapy, drug’s reaction.